Activity Test of Facial Wash Formulation Containing Ethanol Extract of Patikala Fruit (Etlingera elatior) Against the Growth of Propionibacterium acnes

Authors

  • Muthmainnah Thalib Universitas Muhammadiyah Makassar
  • Istianah Purnamasari Universitas Muhammadiyah Makassar
  • Nirwana Nirwana Universitas Muhammadiyah Makassar

DOI:

https://doi.org/10.55606/ijhs.v5i1.6080

Keywords:

Patikala fruit extract (Etlingera elatior), facial wash, antibacterial, Propionibacterium acnes

Abstract

Acne (acne vulgaris) in Indonesia, as a country with a tropical climate, has a high prevalence of the disease. This is caused by tropical climate conditions that support the growth of bacteria, parasites, and fungi. Propionibacterium acnes is another organism involved in skin pathogenesis. One of the plants that has antibacterial properties is the patikala fruit (Etlangiera elatior) as an anti-acne agent so it can be formulated as a facial wash preparation because it has antioxidant and antimicrobial activity. This study aims to determine whether the ethanol extract of the patikala fruit (Etlangiera elatior) can be formulated into a facial wash preparation that has good physical stability and has antibacterial activity at concentrations of 3%, 6% and 9%. This research method is a laboratory experiment that aims to formulate a facial wash preparation based on the ethanol extract of the patikala fruit (Etlangiera elatior) and test its antibacterial activity against the bacteria that causes acne, namely Propionibacterium acnes. The most effective facial wash preparation of ethanol extract of patikala fruit (Etlingera elatior) in inhibiting the growth of Propionibacterium acnes bacteria is a concentration of 9% with an inhibitory power of 16.43 mm, which is included in the strong category.

Downloads

Download data is not yet available.

References

Abdelkader, H. (2018). Effect of temperature stress on rheological properties of ophthalmic gels. International Journal of Pharmaceutics.

An, H. J., Lee, Y., Liu, L., Lee, S., Lee, J. D., & Yi, Y. (2019). Physical and chemical stability of formulations loaded with taxifolin tetra-octanoate. Chemical and Pharmaceutical Bulletin, 67(9), 985–991.

https://doi.org/10.1248/cpb.c19-00283

Bukar, A., Uba, A., & Oyeyi, T. I. (2010). Antimicrobial profile of Moringa oleifera Lam. extracts against some food-borne microorganisms. Bayero Journal of Pure and Applied Sciences, 3(1), 43–48.

https://doi.org/10.4314/bajopas.v3i1.58701

Draelos, Z. D. (2018). The science behind skin care: Moisturizers, cleansers, and anti-acne products. Dermatologic Clinics, 36(2), 107–118.

https://doi.org/10.1016/j.det.2017.11.001

Farida, S., & Maruzy, A. (2016). Kecombrang (Etlingera elatior): A review of traditional use, phytochemical, and pharmacological activity. Indonesian Journal of Medicinal Plants, 9(1), 19–28.

https://doi.org/10.22435/toi.v9i1.6389.19-28

Fahruddin, A. M., Tatengkeng, F., Thamrin, R., Riewpassa, I. E., Klinik, M., & Preklinik, M. (2016). Antibacterial effectiveness of patikala fruit extract (Etlingera elatior (Jack) RMSm) against Enterococcus faecalis. Makassar Dental Journal, 5(3), 69–75.

Kaur, I. P., & Kanwar, M. (2002). Ocular preparations: The formulation approach. Drug Development and Industrial Pharmacy, 28(5), 473–493.

https://doi.org/10.1081/DDC-120003013

Mandal, S. M., Dias, R. O., & Franco, O. L. (2017). Phenolic compounds in antimicrobial therapy. Journal of Medicinal Food, 20(11), 1031–1038.

https://doi.org/10.1089/jmf.2017.0011

Nasri, H., Baradaran, A., Shirzad, H., & Rafieian-Kopaei, M. (2014). New concepts in nutraceuticals as alternative for pharmaceuticals. International Journal of Preventive Medicine, 5(12), 1487–1499.

Nirmala, F. M., Saputri, G. A. R., & Marcellia, S. (2021). Formulation of facial wash preparation combination of lemon juice (Citrus limon (L.)) and tomato fruit extract (Solanum lycopersicum L.) on the inhibitory power of Propionibacterium acnes. Jurnal Mandala Pharmacon Indonesia, 7(2), 188–206.

http://www.jurnal-pharmaconmw.com/jmpi

Sifatullah, N., & Zulkarnain. (2021). Acne (Acne vulgaris): A review of infectious skin diseases. In Proceedings of Biology Achieving the Sustainable Development Goals (pp. 19–23).

Sitorus, F. C. E., Wulansari, E. D., & Sulistyarini, I. (2020). Test of total phenolic content and antibacterial activity of asam paya fruit peel extract (Eleiodoxa conferta (Griff.) Burret) against Staphylococcus aureus. Indonesian Pharmaceutical Media, 15(2), 1617–1624.

Suleman, A. W., Latu, S., Padjalangi, A. M. Y., & Jangga, J. (2024). Activity test of peel-off gel mask formula from ethanol extract of patikala fruit (Etlingera elatior (Jack) RM Smith) against the growth of acne-causing bacteria. Lumbung Farmasi: Journal of Pharmaceutical Sciences, 5(1), 7.

https://doi.org/10.31764/lf.v5i1.14011

Walters, R. M., Mao, G., & Wiechers, J. W. (2012). The science behind skin cleansers. International Journal of Cosmetic Science, 34(4), 343–349.

https://doi.org/10.1111/j.1468-2494.2012.00700.x

Yusran, A., & Muhammad, F. (2018). Inhibitory potency of extract of patikala fruit (Etlingera elatior (Jack) RMSm) on the growth of Staphylococcus aureus. Makassar Dental Journal, 7(2), 95–99.

Downloads

Published

2025-12-05

How to Cite

Muthmainnah Thalib, Istianah Purnamasari, & Nirwana Nirwana. (2025). Activity Test of Facial Wash Formulation Containing Ethanol Extract of Patikala Fruit (Etlingera elatior) Against the Growth of Propionibacterium acnes. International Journal Of Health Science, 5(1), 273–280. https://doi.org/10.55606/ijhs.v5i1.6080