The Relationship between Glycemic Control and Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus

Nasya Amelia Putri; Mohammad Arifin Noor; Suyanto Suyanto

doi:10.55606/ijhs.v6i1.6844

Authors

Nasya Amelia Putri Universitas Islam Sultan Agung
Mohammad Arifin Noor Universitas Islam Sultan Agung
Suyanto Suyanto Universitas Islam Sultan Agung

DOI:

https://doi.org/10.55606/ijhs.v6i1.6844

Keywords:

Blood Sugar Control, Chi-Square, Diabetes Mellitus, Monofilamen, Peripheral Neuropathy

Abstract

People with diabetes mellitus are prone to various complications, uncontrolled blood sugar increases the risk of peripheral neuropathy. The purpose of this study is to determine the relationship between blood sugar control and peripheral neuropathy in patients with type 2 diabetes mellitus. This study employed a quantitative, non-experimental design with a correlational approach. Data were collected using monofilament examinations and a review of medical records. The study involved 104 participants recruited via purposive sampling. Subsequently, data analysis was performed using the Chi-Square test to determine statistical significance. The results of the univariate analysis mostly had characteristics of late elderly at 32,7%, housewife occcupation at 35,6%, BMI indicating overweight at 47,1%, stage 1 hypertension with systolic blood pressure at 35,6%, and stage 2 hypertension with diastholic blood pressure at 31,7%. Uncontrolled blood glucose was 73%, and peripheral neuropathy was 81%. Bivariate analysis yielded a p-value of 0.001 (p < 0.05), indicating a statistically significant relationship between blood sugar control and peripheral neuropathy in patients with Type 2 Diabetes Mellitus.

Downloads

Download data is not yet available.

References

Activah, N., Faradisi, F., & Fijianto, D. (2022). Increased diabetic neuropathy scores and their relationship with body mass index. Urecol Journal. Part C: Health Sciences, 2(1), 9–14. https://doi.org/10.53017/ujhs.133

Aktifah, N., Rahayu, U. B., Setyawan, M. G. M., Faradisi, F., & Fijianto, D. (2023). Analysis of determinant diabetic neuropathy symptom score factors in diabetes mellitus patients. Indonesian Journal of Medicine and Health, 14(3), 274–280. https://doi.org/10.20885/jkki.vol14.iss3.art7

Astuti, A., Merdekawati, D., Octavia, D., & Sari, I. (2023). Diabetic peripheral neuropathy in adults with type 2 diabetes mellitus. Malaysian Journal of Nursing, 14(4), 55–61. https://doi.org/10.31674/mjn.2023.v14i04.006

Billa, M. S., Sulistiawan, A., & Subandi, A. (2023). The relationship between glycemic control and length of diabetes with the incidence of diabetic peripheral neuropathy at Dr. Bratanata Hospital, Jambi City. MAHESA: Malahayati Health Student Journal, 3(6), 1558–1569. https://doi.org/10.33024/mahesa.v3i6.10443

Brutsaert, E. F. (2023). Diabetes mellitus (DM). New York Medical College.

Devi, H. M., Endra Cita, E., & Malo, M. M. (2024). The effect of fasting blood sugar levels, duration of suffering, and stress levels on foot sensitivity of type 2 diabetes mellitus patients. In Proceedings of the National Conference on Nursing (NCN) (Vol. 1, No. 1).

Dinas Kesehatan Provinsi Jawa Tengah. (2023). Profil kesehatan Provinsi Jawa Tengah tahun 2023.

Dube, S., Hulke, S. M., Santosh, L. W., Khadanga, S., Thakare, A. E., Bharshankar, R. N., & Abhijit, P. (2022). Effectiveness of Semmes Weinstein 10 g monofilament in diabetic peripheral neuropathy taking nerve conduction and autonomic function study as reference tests. Journal of Family Medicine and Primary Care, 11(2), 169–170. https://doi.org/10.4103/jfmpc.jfmpc_195_22

Galicia-Garcia, U., Benito-Vicente, A., Jebari, S., & Larrea-Sebal, A. (2020). Costus ignus: Insulin plant and its preparations as a remedial approach for diabetes mellitus. International Journal of Molecular Sciences, 21, 1–34.

Guyanto, M. (2024). Mengenal diabetes mellitus.

Hamid, W. S., Ahmed, H. S., Osman, M. A., & Babiker, R. (2021). Nerve conduction and its correlations with duration of diabetes mellitus and glycosylated hemoglobin in type 2 diabetes mellitus. Journal of Endocrinology, Metabolism and Diabetes of South Africa, 26(2), 46–51. https://doi.org/10.1080/16089677.2021.1877444

Hasyim, H., Wangi, H., & Sartika, S. D. (2023). Risk factors for diabetic neuropathy in type 2 diabetes mellitus patients undergoing outpatient treatment. Bosowa Medical Journal, 1(2), 77–82. https://doi.org/10.56326/bmj.v1i2.2480

Hikmah, N., Mahpolah, & Widyastuti Hariati, N. (2023). The relationship between perception, physical activity, diet, and body mass index with the incidence of type 2 diabetes mellitus. Journal of Food and Nutrition Research, 5(2), 20–32. https://doi.org/10.31964/jr-panzi.v5i2.187

International Diabetes Federation. (2021). IDF diabetes atlas (10th ed.).

Kementerian Kesehatan Republik Indonesia. (2023). Profil kesehatan Indonesia tahun 2023.

Kovatchev, B., & Fabris, C. (2020). Glucose monitoring devices: Measuring blood glucose to manage and control diabetes.

Labib Bima, M. M., Rahmayani, F., & Mutiara, H. (2023). Diagnosis, risk factors, and management of diabetic neuropathy. Medula, 13(April), 59.

Laode, S., Junaiti, S., Rekawati, E., & Ayubi, D. (2022). Self-care of type 2 diabetes mellitus clients with peripheral neuropathy.

Lestari, Zulkarnain, Sijid, & Aisyah, S. (2021). Diabetes mellitus: Review of etiology, pathophysiology, symptoms, examination methods, treatment, and prevention. UIN Alauddin Makassar Journal, 1(2), 237–241.

Lisa, M., Istarini, A., Syauqy, A., Natasha, N., & Shafira, A. (2025). Association between random blood glucose levels and diabetic neuropathy in type 2 diabetes mellitus patients. 41(September).

Luawo, S. H., Sulistiani Basir, I., Mursyidah, A., & Rekan. (2025). The relationship between diabetic neuropathy and sleep quality in type 2 diabetes mellitus patients. Collaborative Journal of Science, 8(6), 3347–3359. https://doi.org/10.56338/jks.v8i6.7762

Pamungkas, R. A., & Usman, A. M. (2021). Practical guide to diabetes and neuropathy risk screening (Vol. 1).

PERKENI. (2021). Pengelolaan dan pencegahan diabetes melitus tipe 2 di Indonesia. PB PERKENI.

Preston, F. G., Riley, D. R., Azmi, S., & Alam, U. (2023). Painful diabetic peripheral neuropathy: Practical guidance and challenges for clinical management. Diabetes, Metabolic Syndrome and Obesity, 16, 1595–1612. https://doi.org/10.2147/DMSO.S370050

Priyantini, D., Ambar, N., Prinka, S., & Hanggitriana, A. (2022). Body mass index in diabetes mellitus patients with ankle brachial index values. Journal of Nursing Science, 17(2), 144–149.

Purwanti, O. S., Istiningrum, A. I., & Wibowo, S. F. (2023). Improving knowledge of people with diabetes mellitus in treating neuropathy. JMM (Jurnal Masyarakat Mandiri), 7(4), 3831. https://doi.org/10.31764/jmm.v7i4.16403

Putri, Y. D., Eltrikanawati, T., & Ariyani. (2022). The relationship between blood sugar levels and peripheral neuropathy disorders in type 2 diabetes mellitus patients.

Qalby, A. A. (2022). The relationship between age, gender, and duration of type 2 diabetes mellitus with early detection value of diabetic neuropathy.

Rosares, V. E., & Boy, E. (2022). Blood sugar level examination for hyperglycemia and hypoglycemia screening. Jurnal Implementa Husada, 3(2), 65–71. https://doi.org/10.30596/jih.v3i2.11906

Shrestha, S., Gorhaly, M. P., & Bajracharya, M. R. (2021). Diagnostic accuracy of monofilament test to detect diabetic neuropathy. Journal of Advances in Internal Medicine, 10(1), 20–25. https://doi.org/10.3126/jaim.v10i1.37086

Suharni, D. T. K., & Zulkarnaini, A. (2022). Characteristics of risk factors for diabetic neuropathy in patients with type 2 diabetes mellitus. Scientific Journal, 1(2), 94–100. https://doi.org/10.56260/sciena.v1i2.38

Tubalawony, S. L., & Parinussa, N. (2023). The relationship between duration of suffering and complications with sleep quality in diabetes mellitus patients. Global Education Scientific Journal, 4(2), 502–508. https://doi.org/10.55681/jige.v4i2.635

Widianti, Zein, A. F. M. Z., & Kusnandang, A. (2024). Factors affecting diabetic neuropathy in patients with type 2 diabetes mellitus. Media Kesehatan, 7(3), 285–294. https://doi.org/10.35990/mk.v7n3.p285-294