The Correlation Between Antiretroviral (ARV) Adherence and Coping Strategies on the Immune Status of People Living with HIV (PLHIV)

Authors

  • Fajar Ibnu Abdulrohman Universitas Islam Sultan Agung
  • Ahmad Ikhlasul Amal Universitas Islam Sultan Agung
  • Dwi Retno Sulistyaningsih Universitas Islam Sultan Agung

DOI:

https://doi.org/10.55606/ijhs.v6i1.6822

Keywords:

ARV Adherence, Coping Strategies, HIV/AIDS, Immune Status, PLHIV

Abstract

Acquired Immune Deficiency Syndrome (AIDS), caused by the Human Immunodeficiency Virus (HIV), remains a significant global health issue, with an estimated 39.9 million people living with HIV (PLHIV) worldwide. HIV damages the immune system, particularly CD4 T cells, making patients susceptible to opportunistic infections. Given this major impact, immune status is a primary focus for PLHIV, where two key factors adherence to Antiretroviral (ARV) therapy and coping strategies play a vital role. ARV adherence is proven to suppress viral replication and restore CD4 cell count, while adaptive coping strategies assist in managing stress that can weaken the immune response. To determine the correlation between ARV adherence and coping strategies on the immune status of people living with HIV (PLHIV). This study used a quantitative research type with a cross-sectional design. The sample consisted of 64 respondents. Sampling was determined using the Slovin formula technique. The data obtained were analyzed using the Spearman's Rho correlation test. The results of the Spearman's Rho correlation test indicated a correlation between antiretroviral (ARV) adherence and coping strategies on the immune status of people living with HIV (PLHIV). There is a correlation between antiretroviral (ARV) adherence and coping strategies on the immune status of people living with HIV (PLHIV).

Downloads

Download data is not yet available.

References

Adiningsih, S., Fitriani, E., & Hidayat, R. (2021). Pengaruh terapi antiretroviral (ARV) terhadap kualitas hidup pasien HIV/AIDS. Jurnal Kesehatan Masyarakat, 3, 45–50.

Berman, E. (2021). The coping process in healthcare: A comprehensive overview. Health Psychology Review.

Dahliyanti, N., Khairiah, R., Nuraidah, & Murtiani, F. (2022). Hubungan kepatuhan antiretroviral therapy dengan status gizi dan kadar CD4 pada anak HIV/AIDS. Jurnal Kesehatan Komunitas, 8(2), 248–256.

Febriani, D. M., Lukas, S., & Murtiani, F. (2025). Evaluasi penggunaan antiretroviral (ARV) berdasarkan indikator CD4 pada pasien HIV di RSPI Prof. Dr. Sulianti Saroso. Artikel Ilmiah, 5(2), 21–30.

Fitriani, A., Indrawati, R., & Puspasari, A. (2022). Compliance to ARV therapy and its impact on life expectancy of HIV patients. Jurnal Infeksi, 1, 34–39.

Glanz, K., & Bishop, D. (2021). Theories of health behavior and health promotion interventions. In Health behavior theories.

Helmiato, S., & AG, T. (2021). Stress and coping mechanisms among HIV/AIDS patients in Indonesia: A case study. Indonesian Journal of Psychology, 1, 101–112.

Hidayati, N. R., Setyaningsih, I., & Pandanwangi, S. (2020). Level of HIV/AIDS patient adherence to the use of antiretroviral (ARV) drugs at RSUD Gunung Jati Cirebon. Jurnal Ilmiah Farmasi, 15(2), 58–66.

Indrawati, R., Fitriani, A., & Rohmawati, D. (2020). Adherence to antiretroviral therapy: A review of factors influencing compliance. Jurnal Penyakit Infeksi, 2, 80–86.

Irwan, Gani, F. M., & Mokodompis, Y. (2025). Kejadian infeksi oportunistik pada orang dengan HIV/AIDS di Kota Gorontalo. Jurnal Kesehatan Masyarakat, 9(2), 119–140.

Jiang, X., Prasetyo, A., & Setiawan, B. (2021). ARV therapy for HIV: Current trends and future directions. Journal of HIV/AIDS Research, 2, 101–110.

Jusriana, Gobel, F. A., & Arman. (2020). Faktor yang berhubungan dengan kepatuhan terapi antiretroviral pada orang dengan HIV di Yayasan Peduli Kelompok Dukungan Sebaya Kota Makassar. Window of Public Health Journal, 1(3), 241–249.

Karyadi, D. (2020). Temulawak and kunyit asam for liver health in HIV patients: A clinical trial. Jurnal Herbal Indonesia, 3, 245–250.

Kementerian Kesehatan Republik Indonesia. (2021). Laporan perkembangan HIV/AIDS di Indonesia. https://www.kemkes.go.id

Manopo, N. A., Pakaya, N., & Rahim, N. K. (2025). Hubungan kepatuhan minum obat ARV dengan kualitas hidup penderita HIV/AIDS. Jurnal Kolaboratif Sains, 8(8), 5504–5512.

Murray, M., Smith, L., & Liu, W. (2020). Antiretroviral therapy in HIV management: A review of effectiveness and guidelines. Clinical Medicine Journal, 4(28), 195–200.

Pranoto. (2020). Stigma and social impact of HIV/AIDS in Indonesia. Jurnal Psikologi Sosial, 1(17), 74–80.

Prasetyo, A., & Setiawan, B. (2021). The impact of early ARV initiation in preventing HIV complications. Jurnal Infeksi dan Terapi, 2(27), 140–148.

Pratiwi, M. E., Atsniyah, L., Tatiana, C., Agustina, E., & Setiowati. (2022). Strategi koping perempuan dengan HIV/AIDS yang terlibat dalam program menulis ekspresif. Jurnal Psikologi Terapan, 8(2), 68–80.

Purnama, H., & Setiawan, T. (2020). The role of antiretroviral therapy in managing HIV/AIDS: Benefits and challenges. Jurnal Kesehatan Indonesia, 4(21), 150–158.

Salami, S., Muvira, A. A., & Yualita, P. (2021). Studi kualitatif strategi koping penderita HIV/AIDS di Kota Bandung. Faletehan Health Journal, 8(1), 22–30.

Sebayang, M. (2020). The role of social support in HIV/AIDS treatment adherence. Jurnal Psikologi Kesehatan, 2(22), 100–108.

Senjaya, S., Hernawaty, T., Hendrawati, & DA, I. A. (2022). Hubungan mekanisme koping dengan status imun pada ODHA selama pandemi COVID-19. Jurnal Riset Ilmiah, 1(4), 1026–1042.

Siam, E. N. (2021). Hubungan antara dukungan keluarga dengan kepatuhan minum obat antiretroviral (ARV) pada orang dengan HIV/AIDS (ODHA) di Puskesmas Dinoyo Kota Malang (Skripsi). Universitas Brawijaya.

Sugiyono. (2021). Metodologi penelitian kuantitatif dan kualitatif. Alfabeta.

Taylor, J. (2024). Stress, coping, and resources: Understanding coping strategies in HIV patients. Journal of Applied Psychology, 3(29), 200–210.

Windiramadhan, A. P., Carsita, W. N., & Rahayu, S. (2024). Hubungan kepatuhan minum obat ARV dengan kualitas hidup orang dengan HIV/AIDS. Artikel Penelitian, 11(1), 1–6.

World Health Organization. (2024). HIV statistics, globally and by WHO region. https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf

Downloads

Published

2026-02-04

How to Cite

Fajar Ibnu Abdulrohman, Ahmad Ikhlasul Amal, & Dwi Retno Sulistyaningsih. (2026). The Correlation Between Antiretroviral (ARV) Adherence and Coping Strategies on the Immune Status of People Living with HIV (PLHIV). International Journal Of Health Science, 6(1), 166–178. https://doi.org/10.55606/ijhs.v6i1.6822